Principal Clinical Scientist

Principal Clinical Scientist (AI Training)

About The Role

What if your career-long expertise in clinical trial design and regulatory science could directly shape how AI understands and reasons about biomedical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to cutting-edge AI research — ensuring the clinical knowledge embedded in next-generation AI systems meets the standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work at the frontier of AI and medicine. No prior AI background needed — just deep domain expertise and a commitment to scientific quality.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
• Provide expert structured feedback to improve how AI models reason about clinical trial data, endpoints, and outcomes
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
• Strong command of clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold clinical evidence to the highest standard
• Clear and concise written communicator who can document reasoning and feedback effectively
• Self-motivated and reliable when working independently

Nice to Have

• Prior experience with data annotation, data quality frameworks, or evaluation systems
• Background in pharmacology, oncology, rare disease, or other specialized therapeutic areas
• Familiarity with AI tools or scientific evaluation workflows
• Experience in medical writing, regulatory affairs, or clinical operations

Why Join Us

• Work directly on frontier AI systems shaping the future of clinical and biomedical research
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, high-impact work
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Collaborate with world-leading AI research teams and labs
• Potential for ongoing work and contract extension as new projects launch